While South Carolina has great quality in coastal golf, I think the greatest place with potential is the Georgia coast. Unfortunately most of the 100 or so miles of oceanfront property is government owned (national seashores, national wildlife refuges). The Georgia coast is so unique though. Cumberland Island, for example, has 60-80 foot tall sand dunes, 300 year old live oaks and beautiful salt marshes. Every time I see the amazing beaches and duneslands that Georgia possesses part of me wishes that SOME HOW, SOME WAY somebody would take advantage of the great natural properties; of course the other part of me knows that some places are just too special to mess with. A little bit of the Georgia coast is privately owned, but I have never heard of anyone expressing desire to develop it.
Another possibility that has always attracted me is the panhandle of Florida. While Destin and Panama City are already overdeveloped (and are still using the oceanfront property for condos and not golf), once you move east of Panama City the coast gets far less developed. The Air Force Base on the east side of Panama City owns miles of totally undeveloped and largely unused oceanfront property. Moving east from the base one finds Mexico Beach, Port St. Joe, Cape San Blas, St. George Island (which originally had an oceanfront golf course in its master plan, but was scrapped for more beachfront housing) and Carabelle Beach. This area is SO much less developed than the cities west of the Air Force Base. As the panhandle continues to develop quickly (see seaside, rosemary beach, camp creek, shark's tooth) I hope that someone will have the foresight to set aside enough land and build what could be a spectacular golf course!